Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes
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چکیده ندارد.
Fatty acid receptor GPR120: its potential role in islet function and Type 2 diabetes mellitus FaTTy aciD rEcEpTor Gpr120’s poTEnTial rolE in islET FuncTion & TypE 2 DiabETEs MElliTus lEunG
2014 Diabetes mellitus is a chronic disease that represents a major socioeconomic burden worldwide; approximately 90–95% of patients are diagnosed as Type 2 diabetes mellitus (T2DM) among the new cases of diabetes. Pancreatic islet β-cell failure is one of the key features of T2DM, which is resultant from chronic hyperglycemia and hyperlipidemia, thus eventually leading to β-cell insulin secret...
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ژورنال
عنوان ژورنال: ACS Medicinal Chemistry Letters
سال: 2017
ISSN: 1948-5875,1948-5875
DOI: 10.1021/acsmedchemlett.7b00233